Kwizera was born in a family of seven boys and one girl. The 18-year-old is a telecommunication engineering student at the Association of the Parents for the Promotion of the Education in Rwanda (APAPER), in Kacyiru, and he is a resident painter at the Niyo Art Gallery and a dance trainer with Niyo Cultural Center, in Kacyiru.

Kwizera started painting at the  tender age of four and since then he has never looked back.
To improve on his skills, Kwizera started visiting Ivuka Arts where he could interact with different artists.
In 2012, when brothers Emmanuel Nkuranga and Innocent Nkurunziza moved from Ivuka Arts to form Inema Art Centre in Kacyiru, Kwizera shifted with them. It's at Inema Arts Center, that he created his own style inspired by women he saw in the neighbourhood carrying babies on the backs and heavy stuff on their heads.
The same year, he sold his first painting at $50. This piece was unfinished, so I felt like even if I did 100 paintings, I would sell them," he recollects.  Before he starts on a painting, he always knows how it will come out; in spite of the fact they are abstract in nature. Sometimes he paints according to the orders placed.